There may be significance outside the realm of numerology. But there is a connection with the number 7. It was your uncle's power number.

The power number 7 tells me that during the last half of his life your uncle looked inward for answers, utilized his keen mind, and had a connection with ancient wisdom.

The number 7 an introspective number. Also a spiritual number. And intuitive. It's a number of analysis, where things generally are thought through before accepting conclusions. Thus, there's an accumulation of wisdom.

Your uncle's destiny number, however, was a 5. It tells me your uncle was expressive, especially when it comes to personal freedom. He generally enjoyed meeting new people, learning about new cultures, travel, writing, pretty much anything that provided a new experience.